5,10-metilentetrahidrometanopterin reduktaza
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| 5,10-metilentetrahidrometanopterin reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.99.11 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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5,10-metilentetrahidrometanopterin reduktaza (EC 1.5.99.11, 5,10-metilintetrahidrometanopterinska ciklohidrolaza, N5,N10-metilintetrahidrometanopterinska reduktaza, metilin-H4MPT reduktaza, koenzim F420-zavisna N5,N10-meteniltetrahidrometanopterinska reduktaza, N5,N10-metilintetrahidrometanopterin:koenzim-F420 oksidoreduktaza) je enzim sa sistematskim imenom 5-metiltetrahidrometanopterin:koenzim-F420 oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 5-metiltetrahidrometanopterin + koenzim F420 5,10-metilintetrahidrometanopterin + redukovani koenzim F420
Ovaj enzim katalizuje intermedijerni korak u metanogenezi iz CO2 i H2 kod bakterija.
Reference[uredi | uredi kod]
- ↑ Ma, K. and Thauer, R.K. (1990). „Purification and properties of N5,N10-methylenetetrahydromethanopterin reductase from Methanobacterium thermoautotrophicum (strain Marburg)”. Eur. J. Biochem. 191: 187-193. PMID 2379499.
- ↑ te Brömmelstroet, B.W., Geerts, W.J., Keltjens, J.T., van der Drift, C. and Vogels, G.D. (1991). „Purification and properties of 5,10-methylenetetrahydromethanopterin dehydrogenase and 5,10-methylenetetrahydromethanopterin reductase, two coenzyme F420-dependent enzymes, from Methanosarcina barkeri”. Biochim. Biophys. Acta 1079: 293-302. PMID 1911853.
- ↑ Ma, K. and Thauer, R.K. (1990). „Single step purification of methylenetetrahydromethanopterin reductase from Methanobacterium thermoautotrophicum by specific binding to blue sepharose CL-6B”. FEBS Lett. 268: 59-62. PMID 1696553.
- ↑ te Brömmelstroet, B.W., Hensgens, C.M., Keltjens, J.T., van der Drift, C. and Vogels, G.D. (1990). „Purification and properties of 5,10-methylenetetrahydromethanopterin reductase, a coenzyme F420-dependent enzyme, from Methanobacterium thermoautotrophicum strain ΔH*”. J. Biol. Chem. 265: 1852-1857. PMID 2298726.
- ↑ te Brömmelstroet, B.W., Hensgens, C.M., Geerts, W.J., Keltjens, J.T., van der Drift, C. and Vogels, G.D. (1990). „Purification and properties of 5,10-methenyltetrahydromethanopterin cyclohydrolase from Methanosarcina barkeri”. J. Bacteriol. 172: 564-571. PMID 2298699.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.