3-metilbutanal reduktaza
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| 3-metilbutanal reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.265 | ||||||||
| CAS broj | 214265-44-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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3-metilbutanal reduktaza (EC 1.1.1.265, 3-metilbutanalna reduktaza) je enzim sa sistematskim imenom 3-metilbutanol:NAD(P)+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3-metilbutanol + NAD(P)+ 3-metilbutanal + NAD(P)H + H+
Prečišćeni enzim iz Saccharomyces cerevisiae katalizuje redukciju brojnih aldehida pravog i razgranatog lanca, kao i pojedine aromatične aldehide.
Reference[uredi | uredi kod]
- ↑ van Iersel, M.F.M., Eppink, M.H.M., van Berkel, W.J.H., Rombouts, F.M. and Abee, T. (1997). „Purification and characterization of a novel NADP-dependent branched-chain alcohol dehydrogenase from Saccharomyces cerevisiae”. Appl. Environ. Microbiol. 63: 4079-4082. PMID 9327572.
- ↑ Ven Nedervelde, L., Verlinden, V., Philipp, D. and Debourg, A. (1997). „Purification and characterization of yeast 3-methyl butanal reductases involved in the removal of wort carbonyls during fermentation”. Proc. 26th Congr.-Eur. Brew. Conv.: 447-454.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.