3-Epi-6-deoksokatasteron 23-monooksigenaza
(Preusmjereno sa stranice 3-epi-6-deoksokatasteron 23-monooksigenaza)
| 3-epi-6-deoksokatasteron 23-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.112 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
3-epi-6-deoksokatasteron 23-monooksigenaza (EC 1.14.13.112, citohrom P450 90C1, CYP90D1, CYP90C1) je enzim sa sistematskim imenom 3-epi-6-deoksokatasteron,NADPH:kiseonik oksidoreduktaza (C-23-hidroksilacija).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (1) 3-epi-6-deoksokatasteron + NADPH + H+ + O2 6-dezoksotifasterol + NADP+ + H2O
- (2) (22S,24R)-22-hidroksi-5alfa-ergostan-3-on + NADPH + H+ + O2 3-dehidro-6-deoksoteasteron + NADP+ + H2O
Ovaj enzim učestvuje u biosintezi brasinosteroida.
Reference[uredi | uredi kod]
- ↑ Ohnishi, T., Szatmari, A.M., Watanabe, B., Fujita, S., Bancos, S., Koncz, C., Lafos, M., Shibata, K., Yokota, T., Sakata, K., Szekeres, M. and Mizutani, M. (2006). „C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis”. Plant Cell 18: 3275-3288. PMID 17138693.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.