1-Pirolin-4-hidroksi-2-karboksilatna deaminaza
(Preusmjereno sa stranice 1-pirolin-4-hidroksi-2-karboksilatna deaminaza)
| 1-Pirolin-4-hidroksi-2-karboksilatna deaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.4.22 | ||||||||
| CAS broj | 9054-77-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
1-Pirolin-4-hidroksi-2-karboksilatna deaminaza (EC 3.5.4.22, HPC deaminaza) je enzim sa sistematskim imenom 1-pirolidin-4-hidroksi-2-karboksilat aminohidrolaza (deciklizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 1-pirolidin-4-hidroksi-2-karboksilat + H2O 2,5-dioksopentanoat + NH3
Reference[uredi | uredi kod]
- ↑ Singh, R.M.M. and Adams, E. (1965). „Enzymatic deamination of Δ1-pyrroline-4-hydroxy-2-carboxylate to 2,5-dioxovalerate (α-ketoglutaric semialdehyde)”. J. Biol. Chem. 240: 4344-4351. PMID 5845838.
- ↑ Singh, R.M.M. and Adams, E. (1965). „Isolation and identification of 2,5-dioxovalerate, an intermediate in the bacterial oxidation of hydroxyproline”. J. Biol. Chem. 240: 4352-4356. PMID 5845839.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.