(R)-aminopropanol dehidrogenaza
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| (R)-aminopropanol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.75 | ||||||||
| CAS broj | 37250-13-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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(R)-aminopropanol dehidrogenaza (EC 1.1.1.75, L-aminopropanol dehidrogenaza, 1-aminopropan-2-ol-NAD+ dehidrogenaza, L(+)-1-aminopropan-2-ol:NAD+ oksidoreduktaza, 1-aminopropan-2-ol-dehidrogenaza, DL-1-aminopropan-2-ol: NAD+ dehidrogenaza, L(+)-1-aminopropan-2-ol-NAD+/NADP+ oksidoreduktaza) je enzim sa sistematskim imenom (R)-1-aminopropan-2-ol:NAD+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (R)-1-aminopropan-2-ol + NAD+ aminoaceton + NADH + H+
Za dejstvo ovog enzima je neophodan K+.
Reference[uredi | uredi kod]
- ↑ Dekker, E.E. and Swain, R.R. (1968). „Formation of Dg-1-amino-2-propanol by a highly purified enzyme from Escherichia coli”. Biochim. Biophys. Acta 158: 306-307. PMID 4385233.
- ↑ Turner, J.M. (1966). „Microbial metabolism of amino ketones. Aminoacetone formation from 1-aminopropan-2-ol by a dehydrgenase in Escherichia coli”. Biochem. J. 99: 427-433. PMID 5329339.
- ↑ Turner, J.M. (1967). „Microbial metabolism of amino ketones. L-1-Aminopropan-2-ol dehydrogenase and L-threonine dehydrogenase in Escherichia coli”. Biochem. J. 104: 112-121. PMID 5340733.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.