(R)-4-hidroksifenillaktat dehidrogenaza
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| (R)-4-hidroksifenillaktat dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.222 | ||||||||
| CAS broj | 101754-02-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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(R)-4-hidroksifenillaktat dehidrogenaza (EC 1.1.1.222, (R)-aromatična laktatna dehidrogenaza, D-hidrogenaza, D-arillaktat) je enzim sa sistematskim imenom (R)-3-(4-hidroksifenil)laktat:NAD(P)+ 2-oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (R)-3-(4-hidroksifenil)laktat + NAD(P)+ 3-(4-hidroksifenil)piruvat + NAD(P)H + H+
Takođe deluje, mada sporije, na (R)-3-fenillaktat, (R)-3-(indol-3-il)laktat i (R)-laktat.
Reference[uredi | uredi kod]
- ↑ Bode, R., Lippoldt, A. and Birnbaum, D. (1986). „Purification and properties of D-aromatic lactate dehydrogenase an enzyme involved in the catabolism of the aromatic amino acids of Candida maltosa”. Biochem. Physiol. Pflanzen 181: 189-198.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.