Pinenska sintaza
(Preusmjereno sa stranice (-)-(1S,5S)-pinene synthase)
| Pinenska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.14 | ||||||||
| CAS broj | 110637-20-2&title= 81611-69-0, 110637-20-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Pinenska sintaza (EC 4.2.3.14, beta-geraniolenska sintaza, (-)-(1S,5S)-pinen sintaza, geranildifosfat difosfat lijaza (formira pinen)) je enzim sa sistematskim imenom geranil-difosfat difosfat-lijaza (ciklizacija, formira pinen).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (1) geranil difosfat alfa-pinen + difosfat
- (2) geranil difosfat beta-pinen + difosfat
Rekombinantni enzim iz Abies grandis deluje u prisustvu jona Mn2+ i K+.
Reference[uredi | uredi kod]
- ↑ Bohlmann, J., Steele, C.L. and Croteau, R. (1997). „Monoterpene synthases from grand fir (Abies grandis). cDNA isolation, characterization, and functional expression of myrcene synthase, (-)-(4S)-limonene synthase, and (-)-(1S,5S)-pinene synthase”. J. Biol. Chem. 272: 21784-21792. PMID 9268308.
- ↑ Gijzen, M., Lewinsohn, E. and Croteau, R. (1991). „Characterization of the constitutive and wound-inducible monoterpene cyclases of grand fir (Abies grandis)”. Arch. Biochem. Biophys. 289: 267-273. PMID 1898071.
- ↑ Wagschal, K.C., Pyun, H.J., Coates, R.M. and Croteau, R. (1994). „Monoterpene biosynthesis: isotope effects associated with bicyclic olefin formation catalyzed by pinene synthases from sage (Salvia officinalis)”. Arch. Biochem. Biophys. 308: 477-487. PMID 8109978.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.