UDP-2,3-diacilglukozaminska difosfataza
(Preusmjereno sa stranice UDP-2,3-diacylglucosamine pyrophosphatase)
UDP-2,3-diacilglukozaminska difosfataza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.6.1.54 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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UDP-2,3-diacilglukozaminska difosfataza (EC 3.6.1.54, UDP-2,3-diacilglukozamin hidrolaza, UDP-2,3-diacilglukozamin pirofosfataza, ybbF (gen), lpxH (gen)) je enzim sa sistematskim imenom UDP-2,3-bis((3R)-3-hidroksimiristoil)-alfa-D-glukozamin 2,3-bis((3R)-3-hidroksimiristoil)-beta-D-glukozaminil 1-fosfat fosfohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-2,3-bis[(3R)-3-hidroksimiristoil]-alfa-D-glukozamin + H2O 2,3-bis[(3R)-3-hidroksimiristoil]-beta-D-glukozaminil 1-fosfat + UMP
Ovaj enzim katalizuje jedan od koraka biosinteze lipida A.
- ↑ Babinski, K.J., Ribeiro, A.A. and Raetz, C.R. (2002). „The Escherichia coli gene encoding the UDP-2,3-diacylglucosamine pyrophosphatase of lipid A biosynthesis”. J. Biol. Chem. 277: 25937-25946. PMID 12000770.
- ↑ Babinski, K.J., Kanjilal, S.J. and Raetz, C.R. (2002). „Accumulation of the lipid A precursor UDP-2,3-diacylglucosamine in an Escherichia coli mutant lacking the lpxH gene”. J. Biol. Chem. 277: 25947-25956. PMID 12000771.
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