Propanoil-KoA C-aciltransferaza
(Preusmjereno sa stranice SCPchi)
Propanoil-KoA C-aciltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.3.1.176 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Propanoil-KoA C-aciltransferaza (EC 2.3.1.176, peroksizomalna tiolaza 2, sterolni nosilac protein-chi, SCPchi, PTE-2) je enzim sa sistematskim imenom 3alfa,7alfa,12alfa-trihidroksi-5beta-holanoil-KoA:propanoil-KoA C-aciltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3alfa,7alfa,12alfa-trihidroksi-5beta-holanoil-KoA + propanoil-KoA KoA + 3alfa,7alfa,12alfa-trihidroksi-24-okso-5beta-holestanoil-KoA
Ovaj takođe deluje na dihidroksi-5beta-holestanoil-KoA i druge acil-KoA derivate razgranatog lanca.
- ↑ Pedersen, J.I. and Gustafsson, J. (1980). „Conversion of 3α,7α,12α-trihydroxy-5β-cholestanoic acid into cholic acid by rat liver peroxisomes”. FEBS Lett. 121: 345-348. PMID 7461136.
- ↑ Kase, F., Björkhem, I. and Pedersen, J.I. (1983). „Formation of cholic acid from 3α,7α,12α-trihydroxy-5β-cholestanoic acid by rat liver peroxisomes”. J. Lipid Res. 24: 1560-1567. PMID 6668450.
- ↑ Russell, D.W. (2003). „The enzymes, regulation, and genetics of bile acid synthesis”. Annu. Rev. Biochem. 72: 137-174. PMID 12543708.
- ↑ Falany, C.N., Johnson, M.R., Barnes, S. and Diasio, R.B. (1994). „Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase”. J. Biol. Chem. 269: 19375-19379. PMID 8034703.
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