16S rRNK (guanin527-N7)-metiltransferaza
(Preusmjereno sa stranice RsmG (gene name))
16S rRNK (guanin527-N7)-metiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.1.1.170 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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16S rRNK (guanin527-N7)-metiltransferaza (EC 2.1.1.170, metiltransferaza G ribozomalne RNK male podjedinice, 16S rRNK metiltransferaza RsmG, GidB, rsmG (gen)) je enzim sa sistematskim imenom S-adenozil-L-metionin:16S rRNK (guanin527-N7)-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + guanin527 u 16S rRNK S-adenozil-L-homocistein + N7-metilguanin527 u 16S rRNK
Ovaj enzim specifično metiliše guanin527 u N7 poziciju u 16S rRNK.
- ↑ Okamoto, S., Tamaru, A., Nakajima, C., Nishimura, K., Tanaka, Y., Tokuyama, S., Suzuki, Y. and Ochi, K. (2007). „Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria”. Mol. Microbiol. 63: 1096-1106. PMID 17238915.
- ↑ Romanowski, M.J., Bonanno, J.B. and Burley, S.K. (2002). „Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold”. Proteins 47: 563-567. PMID 12001236.
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