Fenilacetil-KoA 1,2-epoksidaza
(Preusmjereno sa stranice Phenylacetyl-CoA:oxygen oxidoreductase (1,2-epoxidizing))
Fenilacetil-KoA 1,2-epoksidaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.14.13.149 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fenilacetil-KoA 1,2-epoksidaza (EC 1.14.13.149, ring 1,2-fenilacetil-KoA epoksidaza, fenilacetil-KoA monooksigenaza, PaaAC, PaaABC(D)E) je enzim sa sistematskim imenom fenilacetil-KoA:kiseonik oksidoreduktaza (1,2-epoksidacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- fenilacetil-KoA + NADPH + H+ + O2 2-(1,2-epoksi-1,2-dihidrofenil)acetil-KoA + NADP+ + H2O
Ovaj enzim učestvuje u aerobnom katabolizmu fenilacetata kod Escherichia coli i Pseudomonas putida.
- ↑ Teufel, R., Mascaraque, V., Ismail, W., Voss, M., Perera, J., Eisenreich, W., Haehnel, W. and Fuchs, G. (2010). „Bacterial phenylalanine and phenylacetate catabolic pathway revealed”. Proc. Natl. Acad. Sci. USA 107: 14390-14395. PMID 20660314.
- ↑ Grishin, A.M., Ajamian, E., Zhang, L. and Cygler, M. (2010). „Crystallization and preliminary X-ray analysis of PaaAC, the main component of the hydroxylase of the Escherichia coli phenylacetyl-coenzyme A oxygenase complex”. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66: 1045-1049. PMID 20823522.
- ↑ Grishin, A.M., Ajamian, E., Tao, L., Zhang, L., Menard, R. and Cygler, M. (2011). „Structural and functional studies of the Escherichia coli phenylacetyl-CoA monooxygenase complex”. J. Biol. Chem. 286: 10735-10743. PMID 21247899.
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