L-laktat dehidrogenaza (citohrom)
(Preusmjereno sa stranice Mlečna kiselina dehidrogenaza)
L-laktat dehidrogenaza (citohrom) | |||||||||
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Identifikatori | |||||||||
EC broj | 1.1.2.3 | ||||||||
CAS broj | 9078-32-4 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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L-laktat dehidrogenaza (citohrom) (EC 1.1.2.3, mlečna kiselina dehidrogenaza, flavocitohrom b2, L-laktat citohrom c reduktaza, L(+)-laktat:citohrom c oksidoreduktaza, dehidrogenaza, laktat (citohrom), L-laktat citohrom c oksidoreduktaza, laktat dehidrogenaza (citohrom), mlečni citohrom c reduktaza) je enzim sa sistematskim imenom (S)-laktat:fericitohrom-c 2-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (S)-laktat + 2 fericitohrom c piruvat + 2 ferocitohrom c + 2 H+
Ovaj enzim je identičan sa citohromom b2; flavohemoproteinom (FMN).
- ↑ Appleby, C.A. and Morton, R.K. (1959). „Lactic dehydrogenase and cytochrome b2 of baker's yeast. Purification and crystallization”. Biochem. J. 71: 492-499. PMID 13638255.
- ↑ Appleby, C.A. and Morton, R.K. (1959). „Lactic dehydrogenase and cytochrome b2 of baker's yeast. Enzymic and chemical properties of the crystalline enzyme”. Biochem. J. 73: 539-550. PMID 13793977.
- ↑ Bach, S.G., Dixon, M. and Zerfas, L.G. (1946). „Yeast lactic dehydrogenase and cytochrome b2”. Biochem. J. 40: 229-239. PMID 16747991.
- ↑ Nygaard, A.P. (1963). „Lactate dehydrogenases of yeast”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 557-565.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
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