2-Hidroksi-3-keto-5-metiltiopentenil-1-fosfatna fosfataza
(Preusmjereno sa stranice HK-MTPenil-1-P fosfataza)
2-Hidroksi-3-keto-5-metiltiopentenil-1-fosfatna fosfataza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.1.3.87 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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2-Hidroksi-3-keto-5-metiltiopentenil-1-fosfatna fosfataza (EC 3.1.3.87, HK-MTPenil-1-P fosfataza, MtnX, YkrX) je enzim sa sistematskim imenom 2-hidroksi-5-(metiltio)-3-oksopent-1-enil fosfat fosfohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2-hidroksi-5-(metiltio)-3-oksopent-1-enil fosfat + H2O 1,2-dihidroksi-5-(metiltio)pent-1-en-3-on + fosfat
Ovaj enzim učestvuje u putu metioninskog spasavanja kod Bacillus subtilis.
- ↑ Myers, R.W., Wray, J.W., Fish, S. and Abeles, R.H. (1993). „Purification and characterization of an enzyme involved in oxidative carbon-carbon bond cleavage reactions in the methionine salvage pathway of Klebsiella pneumoniae”. J. Biol. Chem. 268: 24785-24791. PMID 8227039.
- ↑ Ashida, H., Saito, Y., Kojima, C., Kobayashi, K., Ogasawara, N. and Yokota, A. (2003). „A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO”. Science 302: 286-290. PMID 14551435.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.