Hanoklavin-I dehidrogenaza
(Preusmjereno sa stranice EC 1.1.1.332)
Hanoklavin-I dehidrogenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.1.1.332 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Hanoklavin-I dehidrogenaza (EC 1.1.1.332, easD (gen), fgaDH (gen)) je enzim sa sistematskim imenom hanoklavin-I:NAD+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hanoklavin-I + NAD+ hanoklavin-I aldehid + NADH + H+
Ovaj enzim katalizuje jedan korak u biosintezi ergot alkaloida kod pojedinih gljiva.
- ↑ Wallwey, C., Matuschek, M. and Li, S.M. (2010). „Ergot alkaloid biosynthesis in Aspergillus fumigatus: conversion of chanoclavine-I to chanoclavine-I aldehyde catalyzed by a short-chain alcohol dehydrogenase FgaDH”. Arch. Microbiol. 192: 127-134. PMID 20039019.
- ↑ Wallwey, C., Heddergott, C., Xie, X., Brakhage, A.A. and Li, S.M. (2012). „Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae”. Microbiology 158: 1634-1644. PMID 22403186.
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