Galaktozildiacilglicerol a-2,3-sijaliltransferaza
(Preusmjereno sa stranice CMP-N-acetil-beta-neuraminat:1,2-diacil-3-beta-D-galaktozil-sn-glicerol N-acetilneuraminiltransferaza)
Galaktozildiacilglicerol a-2,3-sijaliltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.4.99.5 | ||||||||
CAS broj | 80237-98-5 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Galaktozildiacilglicerol a-2,3-sijaliltransferaza (EC 2.4.99.5, Galactosyldiacylglycerol alpha-2,3-sialyltransferase) je enzim sa sistematskim imenom CMP-N-acetil-beta-neuraminat:1,2-diacil-3-beta-D-galaktozil-sn-glicerol N-acetilneuraminiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CMP-N-acetil-beta-neuraminat + 1,2-diacil-3-beta-D-galaktozil-sn-glicerol CMP + 1,2-diacil-3-[3-(N-acetil-alfa-D-neuraminil)-beta-D-galaktozil]-sn-glicerol
Beta-D-galaktozilni ostatak oligosaharida glikoproteina takođe može da deluje kao akceptor.
- ↑ Pieringer, J., Keech, S. and Pieringer, R.A. (1981). „Biosynthesis in vitro of sialosylgalactosyldiacylglycerol by mouse brain microsomes”. J. Biol. Chem. 256: 12306-12309. PMID 7298658.
- ↑ Weinstein, J., de Souza-e-Silva, U. and Paulson, J.C. (1982). „Purification of a Gal β1→4GlcNAc α2→6 sialyltransferase and a Gal β1→3(4)GlcNAc α2→3 sialyltransferase to homogeneity from rat liver”. J. Biol. Chem. 257: 13835-13844. PMID 7142179.
- ↑ Weinstein, J., de Souza-e-Silva, U. and Paulson, J.C. (1982). „Sialylation of glycoprotein oligosaccharides N-linked to asparagine. Enzymatic characterization of a Gal β1→3(4)GlcNAc α2→3 sialyltransferase and a Gal β1→4GlcNAc α2→6 sialyltransferase from rat liver”. J. Biol. Chem. 257: 13845-13853. PMID 7142180.
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