4-(Citidin 5'-difosfo)-2-C-metil-D-eritritol kinaza
(Preusmjereno sa stranice 4-(citidin 5'-difosfo)-2-C-metil-D-eritritol kinaza)
4-(Citidin 5'-difosfo)-2-C-metil-D-eritritol kinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.1.148 | ||||||||
CAS broj | 263016-77-9 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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4-(Citidin 5'-difosfo)-2-C-metil-D-eritritol kinaza (EC 2.7.1.148, CDP-ME kinaza) je enzim sa sistematskim imenom ATP:4-(citidin 5'-difosfo)-2-C-metil-D-eritritol 2-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + 4-(citidin 5'-difosfo)-2-C-metil-D-eritritol ADP + 2-fosfo-4-(citidin 5'-difosfo)-2-C-metil-D-eritritol
Za rad enzima iz Escherichia coli je neophodan jon Mg2+ ili Mn2+.
- ↑ Lüttgen, H., Rohdich, F., Herz, S., Wungsintaweekul, J., Hecht, S., Schuhr, C.A., Fellermeier, M., Sagner, S., Zenk, M.H., Bacher, A. and Eisenreich, W. (2000). „Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erithritol”. Proc. Natl. Acad. Sci. USA 97: 1062-1067. PMID 10655484.
- ↑ Kuzuyama, T., Takagi, M., Kaneda, K., Watanabe, H., Dairi, T. and Seto, H. (2000). „Studies on the nonmevalonate pathway: conversion of 4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol to its 2-phospho derivative by 4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol kinase”. Tetrahedron Lett. 41: 2925-2928.
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