Undekaprenilna difosfataza

Izvor: Wikipedia
Undekaprenilna difosfataza
Identifikatori
EC broj 3.6.1.27
CAS broj 9077-80-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Undekaprenilna difosfataza (EC 3.6.1.27, C55-izoprenilna difosfataza, C55-izoprenilna pirofosfataza, izoprenilna pirofosfataza, undekaprenil pirofosfatna fosfataza, undekaprenil pirofosfatna pirofosfataza, UPP fosfataza, Und-PP pirofosfataza, UppP, BacA, undekaprenil-difosfatna fosfohidrolaza, undekaprenil-difosfataza) je enzim sa sistematskim imenom ditrans,oktacis-undekaprenil-difosfat fosfohidrolaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju

ditrans,oktacis-undekaprenil difosfat + H2O \rightleftharpoons ditrans,oktacis-undekaprenil fosfat + fosfat

Ovaj enzim je izolovan iz bakterija Micrococcus lysodeikticus, Escherichia coli i Bacillus subtilis.

Reference[uredi - уреди]

  1. Goldman, R. and Strominger, J.L. (1972). "Purification and properties of C55-isoprenylpyrophosphate phosphatase from Micrococcus lysodeikticus". J. Biol. Chem. 247: 5116–5122. PMID 4341539. 
  2. El Ghachi, M., Bouhss, A., Blanot, D. and Mengin-Lecreulx, D. (2004). "The bacA gene of Escherichia coli encodes an undecaprenyl pyrophosphate phosphatase activity". J. Biol. Chem. 279: 30106–30113. PMID 15138271. 
  3. El Ghachi, M., Derbise, A., Bouhss, A. and Mengin-Lecreulx, D. (2005). "Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli". J. Biol. Chem. 280: 18689–18695. PMID 15778224. 
  4. Bernard, R., El Ghachi, M., Mengin-Lecreulx, D., Chippaux, M. and Denizot, F. (2005). "BcrC from Bacillus subtilis acts as an undecaprenyl pyrophosphate phosphatase in bacitracin resistance". J. Biol. Chem. 280: 28852–28857. PMID 15946938. 
  5. Tatar, L.D., Marolda, C.L., Polischuk, A.N., van Leeuwen, D. and Valvano, M.A. (2007). "An Escherichia coli undecaprenyl-pyrophosphate phosphatase implicated in undecaprenyl phosphate recycling". Microbiology 153: 2518–2529. PMID 17660416. 
  6. Touze, T., Blanot, D. and Mengin-Lecreulx, D. (2008). "Substrate specificity and membrane topology of Escherichia coli PgpB, an undecaprenyl pyrophosphate phosphatase". J. Biol. Chem. 283: 16573–16583. PMID 18411271. 

Literatura[uredi - уреди]

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