Tritokvalin

Tritokvalin
(IUPAC) ime
	7-amino-4,5,6-trietoksi-3-(4-metoksi-6-metil-7,8-dihidro-5H-[1,3]dioksolo[4,5-g]izohinolin-5-il)-3H-izobenzofuran-1-on
Klinički podaci
AHFS/Drugs.com	Internacionalno ime leka
Identifikatori
CAS broj	14504-73-5
ATC kod	R06AX21
PubChem	72145
ChemSpider	65119
UNII	F4MW5166YH
Hemijski podaci
Formula	C26H32N2O8
Mol. masa	500,54 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C26H32N2O8/c1-6-31-23-17-16(18(27)24(32-7-2)25(23)33-8-3)26(29)36-21(17)19-15-13(9-10-28(19)4)11-14-20(22(15)30-5)35-12-34-14/h11,19,21H,6-10,12,27H2,1-5H3 ; Key: IRGJVQIJENCTQF-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Tritokvalin (hipostamin) je inhibitor enzima histidinska dekarboksilaza i stoga je atipičan antihistaminik. On se koristi za tretiranje koprivnjače i alergijskog rinitisa^[4] bez poznatih nuspojava.

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Randomized, placebo controlled study of tritoqualine (hypostamine*) in the treatment of perennial allergic rhinitis. A. Pradalier, V. Hentschel, S. Prouzeau, D. Legallais, G. Lefrançois. Revue Française d’Allergologie et d’Immunologie Clinique 43:175-179 (2003)

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