Treonin-fosfatna dekarboksilaza

Izvor: Wikipedia
Treonin-fosfatna dekarboksilaza
Identifikatori
EC broj 4.1.1.81
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Treonin-fosfatna dekarboksilaza (EC 4.1.1.81, L-treonin-O-3-fosfat dekarboksilaza, CobD, L-treonin-O-3-fosfat karboksilijaza) je enzim sa sistematskim imenom L-treonin-O-3-fosfat karboksilijaza (formira (R)-1-aminopropan-2-il-fosfat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

L-treonin O-3-fosfat \rightleftharpoons (R)-1-aminopropan-2-il fosfat + CO2

Ovaj enzim je piridoksal-fosfatni protein.

Reference[uredi - уреди]

  1. Cheong, C.G., Bauer, C.B., Brushaber, K.R., Escalante-Semerena, J.C. and Rayment, I. (2002). "Three-dimensional structure of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica". Biochemistry 41: 4798–4808. PMID 11939774. 
  2. Brushaber, K.R., O'Toole, G.A. and Escalante-Semerena, J.C. (1998). "CobD, a novel enzyme with L-threonine-O-3-phosphate decarboxylase activity, is responsible for the synthesis of (R)-1-amino-2-propanol O-2-phosphate, a proposed new intermediate in cobalamin biosynthesis in Salmonella typhimurium LT2". J. Biol. Chem. 273: 2684–2691. PMID 9446573. 
  3. Warren, M.J., Raux, E., Schubert, H.L. and Escalante-Semerena, J.C. (2002). "The biosynthesis of adenosylcobalamin (vitamin B12)". Nat. Prod. Rep. 19: 390–412. PMID 12195810. 

Literatura[uredi - уреди]

Spoljašnje veze[uredi - уреди]