SpoIVB peptidaza
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| SpoIVB peptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.116 | ||||||||
| CAS broj | 296241-18-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
SpoIVB peptidaza (EC 3.4.21.116, proteaza sporulacionog faktora IV B) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Samopresencanje Val52-Asn53, Ala62-Phe63 i Val74-Thr75 na N-terminusu SpoIVB
Ovaj enzim ima centralnu ulogu u regulaciji izražavanja gena tokom kasnijih stupnjeva formiranja spora kod bakterije Bacillus subtilis.
Reference[uredi | uredi kod]
- ↑ Wakeley, P.R., Dorazi, R., Hoa, N.T., Bowyer, J.R. and Cutting, S.M. (2000). „Proteolysis of SpolVB is a critical determinant in signalling of pro-σK processing in Bacillus subtilis”. Mol. Microbiol. 36: 1336-1348. PMID 10931284.
- ↑ Hoa, N.T., Brannigan, J.A. and Cutting, S.M. (2001). „The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions”. J. Bacteriol. 183: 4364-4373. PMID 11418578.
- ↑ Hoa, N.T., Brannigan, J.A. and Cutting, S.M. (2002). „The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases”. J. Bacteriol. 184: 191-199. PMID 11741860.
- ↑ Dong, T.C. and Cutting, S.M. (2003). „SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of pro-σK in Bacillus subtilis”. Mol. Microbiol. 49: 1425-1434. PMID 12940997.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.