Rošov estar
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| Rošov estar | |||
|---|---|---|---|
| |||
| IUPAC ime |
| ||
| Identifikacija | |||
| CAS registarski broj | 72657-23-9 (R), 80657-57-4 (S) | ||
| PubChem[1][2] | 24856357, 24856356 | ||
| Svojstva | |||
| Molekulska formula | C5H10O3 | ||
| Molarna masa | 118,13 gmol-1 | ||
| Gustina | 1.071 g/mL | ||
| Tačka ključanja |
74°C at 10 mmHg | ||
| Opasnost | |||
| Tačka paljenja | 80°C (176°F) | ||
|
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| Infobox references | |||
Rošov estar (metil 3-hidroksi-2-metilpropionat) je hemijsko jedinjenje sa formulom C5H10O3. On se javlja u obliku dva enantiomera. Oba su komercijalno dostupna i nalaze široku primenu kao početni blokovi za sintezu mnogih jedinjenja uključujući diktiostatin,[3] diskodermolid[4] i spongidepsin.[5]
Reference[uredi | uredi kod]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Shin, Youseung; Fournier, Jean-Hugues; Fukui, Yoshikazu; Brückner, Arndt; Curran, Dennis (2004). „Total Synthesis of (−)-Dictyostatin: Confirmation of Relative and Absolute Configurations”. Angewandte Chemie International Edition (Wiley) 43 (35): 4634–4637. DOI:10.1002/anie.200460593.
- ↑ Paterson, Ian; Florence, Gordon (2003). „The Development of a Practical Total Synthesis of Discodermolide, a Promising Microtubule-Stabilizing Anticancer Agent”. European Journal of Organic Chemistry (Wiley) (12): 2193–2208. DOI:10.1002/ejoc.200300061.
- ↑ Ferrié, Laurent; Reymond, Sébastien; Capdevielle, Patrice; Cossy, Janine (2006). „Total Synthesis of (−)-Spongidepsin”. Organic Letters (American Chemical Society) 8 (16): 3441–3443. DOI:10.1021/ol061029w.
