Represor LexA
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| Represor LexA | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 3.4.21.88 | ||||||||
| CAS broj | 84721-00-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Represor LexA (EC 3.4.21.88, LexA represor) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza Ala84-Gly veze u represoru LexA
Za aktivnot ovog enzim su neophodni RecA protein i jednolančana DNK.
Reference[uredi | uredi kod]
- ↑ Horii, T., Ogawa, T. and Ogawa, H. (1981). „Nucleotide sequence of the LexA gene of E. coli”. Cell 23: 689-697. PMID 7013987.
- ↑ Slilaty, S.N. and Little, J.W. (1987). „Lysine-156 and serine-119 are required for LexA repressor cleavage: a possible mechanism”. Proc. Natl. Acad. Sci. USA 84: 3987-3991. PMID 3108885.
- ↑ Kim, B. and Little, J.W. (1993). „LexA and CI repressors as enzymes: specific cleavage in an intermolecular reaction”. Cell 73: 1165-1173. PMID 8513500.
- ↑ Little, J.W., Kim, B., Roland, K.L., Smith, M.H., Lin, L.-L. and Slilaty, S.N. (1994). „Cleavage of LexA repressor”. Methods Enzymol. 244: 266-284. PMID 7845214.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.