Putidaredoksin-NAD+ reduktaza
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| Putidaredoksin-NAD+ reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.18.1.5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Putidaredoksin-NAD+ reduktaza (EC 1.18.1.5, putidaredoksinska reduktaza, camA (gen)) je enzim sa sistematskim imenom putidaredoksin:NAD+ oksidoreduktaza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- redukovani putidaredoksin + NAD+ oksidovani putidaredoksin + NADH + H+
Za rad ovog enzima je neophodan FAD. Enzim iz Pseudomonas putida redukuje putidaredoksin.
Reference[uredi | uredi kod]
- ↑ Roome, P.W., Jr., Philley, J.C. and Peterson, J.A. (1983). „Purification and properties of putidaredoxin reductase”. J. Biol. Chem. 258: 2593-2598. PMID 6401738.
- ↑ Koga, H., Yamaguchi, E., Matsunaga, K., Aramaki, H. and Horiuchi, T. (1989). „Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida”. J. Biochem. 106: 831-836. PMID 2613690.
- ↑ Peterson, J.A., Lorence, M.C. and Amarneh, B. (1990). „Putidaredoxin reductase and putidaredoxin. Cloning, sequence determination, and heterologous expression of the proteins”. J. Biol. Chem. 265: 6066-6073. PMID 2180940.
- ↑ Sevrioukova, I.F. and Poulos, T.L. (2002). „Putidaredoxin reductase, a new function for an old protein”. J. Biol. Chem. 277: 25831-25839. PMID 12011076.
- ↑ Sevrioukova, I.F., Garcia, C., Li, H., Bhaskar, B. and Poulos, T.L. (2003). „Crystal structure of putidaredoxin, the [2Fe-2S] component of the P450cam monooxygenase system from Pseudomonas putida”. J. Mol. Biol. 333: 377-392. PMID 14529624.
- ↑ Sevrioukova, I.F., Li, H. and Poulos, T.L. (2004). „Crystal structure of putidaredoxin reductase from Pseudomonas putida, the final structural component of the cytochrome P450cam monooxygenase”. J. Mol. Biol. 336: 889-902. PMID 15095867.
- ↑ Smith, N., Mayhew, M., Holden, M.J., Kelly, H., Robinson, H., Heroux, A., Vilker, V.L. and Gallagher, D.T. (2004). „Structure of C73G putidaredoxin from Pseudomonas putida”. Acta Crystallogr. D Biol. Crystallogr. 60: 816-822. PMID 15103126.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.