Polienoinska masno kiselinska izomeraza

Izvor: Wikipedia
Polienoinska masno kiselinska izomeraza
Identifikatori
EC broj 5.3.3.13
CAS broj 159002-84-3
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Polienoinska masno kiselinska izomeraza (EC 5.3.3.13, PFI, eikosapentaenoat cis-Delta5,8,11,14,17-eikosapentaenoat cis-Delta5-trans-Delta7,9-cis-Delta14,17 izomeraza, (5Z,8Z,11Z,14Z,17Z)-eikosapentaenoat Delta8,11-Delta7,8-izomeraza, (5Z,8Z,11Z,14Z,17Z)-eikosapentaenoat Delta8,11-Delta7,9-izomeraza (formira trans dvostruku vezu)) je enzim sa sistematskim imenom (5Z,8Z,11Z,14Z,17Z)-ikosapentaenoat Delta8,11-Delta7,9-izomeraza (formira trans dvostruku vezu).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

(5Z,8Z,11Z,14Z,17Z)-ikosapentaenoat \rightleftharpoons (5Z,7E,9E,14Z,17Z)-ikosapentaenoat

Enzim iz crvene alge Ptilota filicina katalizuje izomerizaciju diena.

Reference[uredi - уреди]

  1. Wise, M.L., Hamberg, M. and Gerwick, W.H. (1994). "Biosynthesis of conjugated fatty acids by a novel isomerase from the red marine alga Ptilota filicina". Biochemistry 33: 15223–15232. PMID 7803384. 
  2. Wise, M.L., Soderstrom, K., Murray, T.F. and Gerwick, W.H. (1996). "Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid". Experientia 52: 88–92. PMID 8575565. 
  3. Wise, M.L., Rossi, J. and Gerwick, W.H. (1997). "Binding site characterization of polyenoic fatty-acid isomerase from the marine alga Ptilota filicina". Biochemistry 36: 2985–2992. PMID 9062129. 
  4. Zheng, W., Wise, M.L., Wyrick, A., Metz, J.G., Yuan, L. and Gerwick, W.H. (2002). "Polyenoic fatty-acid isomerase from the marine red alga Ptilota filicina: protein characterization and functional expression of the cloned cDNA". Arch. Biochem. Biophys. 401: 11–20. PMID 12054482. 

Literatura[uredi - уреди]

Spoljašnje veze[uredi - уреди]