Pirimidin-nukleozid fosforilaza

Izvor: Wikipedia
Pirimidin-nukleozid fosforilaza
Identifikatori
EC broj 2.4.2.2
CAS broj 9055-35-0
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Pirimidin-nukleozid fosforilaza (EC 2.4.2.2, Py-NPase) je enzim sa sistematskim imenom pirimidin-nukleozid:fosfat alfa-D-riboziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

pirimidin nukleozid + fosfat \rightleftharpoons pirimidinska baza + alfa-D-riboza 1-fosfat

Uridin i timidin su supstrati.

Reference[uredi - уреди]

  1. Friedkin, M. and Kalckar, H. (1961). "Nucleoside phosphorylases". u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 5 (2nd izd.). New York: Academic Press. str. 237-255. 
  2. Saunders, P.P., Wilson, B.A. and Saunders, G.F. (1969). "Purification and comparative properties of a pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus". J. Biol. Chem. 244: 3691–3697. PMID 4978445. 
  3. Hamamoto, T., Noguchi, T. and Midorikawa, Y. (1996). "Purification and characterization of purine nucleoside phosphorylase and pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus TH 6-2". Biosci. Biotechnol. Biochem. 60: 1179–1180. PMID 8782414. 

Literatura[uredi - уреди]

  • Friedkin, M. and Kalckar, H. (1961). "Nucleoside phosphorylases". u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 5 (2nd izd.). New York: Academic Press. str. 237-255. 

Spoljašnje veze[uredi - уреди]