Pikornain 2A
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| Pikornain 2A | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.29 | ||||||||
| CAS broj | 103406-62-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Pikornain 2A (EC 3.4.22.29, pikornavirusna endopeptidaza 2A, poliovirusna proteaza 2A, rinovirusna proteaza 2A, 2A proteaza, 2A proteinaza, proteaza 2A, proteinaza 2Apro, pikornaviralna 2A proteinaza, Y-G proteinaza 2A, poliovirusna proteinaza 2A, poliovirusna proteaza 2Apro, pikornaviralna 2A proteinaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Selektivno razlaganje Tyr-Gly veze u pilornavirusnom poliproteinu
Ovaj enzim izražavaju entero-, rino-, afto- i kardiovirusi.
Reference[uredi | uredi kod]
- ↑ Bazan, J.F. and Fletterick, R.J. (1988). „Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications”. Proc. Natl Acad. Sci. USA 85: 7872-7876. PMID 3186696.
- ↑ König, H. and Rosenwirth, B. (1988). „Purification and partial characterization of poliovirus protease 2A by means of a functional assay”. J. Virol. 62: 1243-1250. PMID 2831385.
- ↑ Kräusslich, H.-G. and Wimmer, E. (1988). „Viral proteinases”. Annu. Rev. Biochem. 57: 701-754. PMID 3052288.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.