Peptidil-Lys metaloendopeptidaza
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| Peptidil-Lys metaloendopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.20 | ||||||||
| CAS broj | 65979-41-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Peptidil-Lys metaloendopeptidaza (EC 3.4.24.20, Armillaria mellea neutralna proteinaza, peptidilnalizinska metaloproteinaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Preferentno razlaganje proteina: -Xaa-Lys (gde Xaa može da bude Pro)
Ovaj enzim je prisutan u gljivi Armillaria mellea.
Reference[uredi | uredi kod]
- ↑ Doonan S, Doonan HJ, Hanford R, Vernon CA, Walker JM, da Airold LP, Bossa F, Barra D, Carloni M, Fasella P, Riva F. (1975). „The primary structure of aspartate aminotransferase from pig heart muscle. Digestion with a proteinase having specificity for lysine residues”. Biochem. J. 149: 497-506. PMID 1239277.
- ↑ Lewis, W.G., Basford, J.M. and Walton, P.L. (1978). „Specificity and inhibition studies of Armillaria mellea protease”. Biochim. Biophys. Acta 522: 551-560. PMID 23849.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.