Pelagra

Izvor: Wikipedia
Pelagra
Klasifikacija i spoljašnji resursi

Osoba obolesa od pelagre sa ranama kože
ICD-10 E52.
ICD-9 265.2
DiseasesDB 9730
MedlinePlus 000342
eMedicine ped/1755
MeSH C18.654.521.500.133.699.529

Pelagra je bolest vitaminske deficijencje, koja je najčešće uzrokovana hroničnim nedostatkom nijacina (vitamina B3) u ishrani. Ona može da bude uzrokava umanjenim unosim niacina ili triptofana,[1] kao i prekomernim unosim leucina.[2] Bolest takođe može da bude rezult promena proteinskog metabolizma usled poremećaja kao što je karcinoidni sindrom. Deficijencja aminokiseline lizina isto tako može da dovede do nedostatka niacina.[3]

Pelagra izaziva oštećenja nervnog sistema, promenu boje koze, ...

Reference[uredi - уреди]

  1. Pitche P (2005). "Pellagra". Sante 15 (3): 205–8. PMID 16207585. 
  2. Bapurao S, Krishnaswamy K (1978). "Vitamin B6 nutritional status of pellagrins and their leucine tolerance". Am J Clin Nutr 31 (5): 819–24. PMID 206127. 
  3. "Lysine | amino acid health benefits, dietary sources, side effects". Vitamins-supplements.org. http://www.vitamins-supplements.org/amino-acids/lysine.php. pristupljeno 2012-07-31. 

Literatura[uredi - уреди]

  • Hampl JS, Hampl WS (1 November 1997). "Pellagra and the origin of a myth: evidence from European literature and folklore". Journal of the Royal Society of Medicine 90 (11): 636–9. PMID 9496281. 
  • (1916) "Reports and Resolutions of the General Assembly of the State of South Carolina, Regular Session Commencing January 11, 1916". Annual Report of the State Board of Health (1915-1916). 4 (Gonzales and Bryan, state printers). 
  • Beardsley E (2006). The Spartanburg Pellagra Hospital. In: The South Carolina Encyclopedia. Columbia, S.C: University of South Carolina Press. ISBN 1-57003-598-9. 
  • Swain CP, Tavill AS, Neale G (September 1976). "Studies of tryptophan and albumin metabolism in a patient with carcinoid syndrome, pellagra, and hypoproteinemia". Gastroenterology 71 (3): 484–9. PMID 133045. 
  • Hendrick, Burton J. (April 1916). "The Mastery Of Pellagra: The Mysterious Disease, Almost Unknown In This Country Fifteen Years Ago, That Now Claims 7,500 Victims A Year And Is Spreading Rapidly". The World's Work: A History of Our Time XXXI: 633–639. pristupljeno na 2009-08-04. 
  • Kraut, Alan. "Dr. Joseph Goldberger and the War on Pellagra, By Alan Kraut, Ph.D." Office of History, National Institutes of Health. Web. 03 Sept. 2010. <http://history.nih.gov/exhibits/goldberger/docs/pellegra_5.htm>.

Vanjske veze[uredi - уреди]

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