Omptin
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| Omptin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.23.49 | ||||||||
| CAS broj | 150770-86-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Omptin (EC 3.4.23.49, proteaza VII, proteaza A, gen ompT protein, ompT proteaza, protein a, Pla, proteaza VII, proteaza A) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Preferentno razlaganje veze: -Xaa-Yaa- u kojoj su Xaa i Yaa: Lys ili Arg
Ovaj enzim je produkt ompT gena bakterije Escherichia coli.
Reference[uredi | uredi kod]
- ↑ Grodberg, J., Lundrigan, M.D., Toledo, D.L., Mangel, W.F. and Dunn, J.J. (1988). „Complete nucleotide sequence and deduced amino acid sequence of the ompT gene of Escherichia coli K-12”. Nucleic Acids Res. 16: 1209-1209. PMID 3278297.
- ↑ Sugimura, K. and Nishihara, T. (1988). „Purification, characterization, and primary structure of Escherichia coli protease VII with specificity for paired basic residues: identity of protease VII and ompT”. J. Bacteriol. 170: 5625-5632. PMID 3056908.
- ↑ Hanke, C., Hess, J., Schumacher, G. and Goebel, W. (1992). „Processing by OmpT of fusion proteins carrying the HlyA transport signal during secretion by the Escherichia coli hemolysin transport system”. Mol. Gen. Genet. 233: 42-48. PMID 1603076.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.