Omega amidaza
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| Omega amidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.3 | ||||||||
| CAS broj | 9025-19-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Omega amidaza (EC 3.5.1.3, alfa-keto kiselina-omega-amidaza) je enzim sa sistematskim imenom omega-amidodikarboksilat amidohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Monoamid dikarboksilne kiseline + H2O dikarboksilat + NH3
Ovaj enzim deluje na glutaramat, sukcinamat i njihove 2-okso derivate.
Reference[uredi | uredi kod]
- ↑ Meister, A., Levintow, L., Greenfield, R.E. and Abendschein, P.A. (1955). „Hydrolysis and transfer reactions catalyzed by ω-amidase preparations”. J. Biol. Chem. 215: 441-460. PMID 14392177.
- ↑ Meister, A., Radhakrishnan, A.N. and Buckley, S.D. (1957). „Enzymatic synthesis of L-pipecolic acid and L-proline”. J. Biol. Chem. 229: 789-800. PMID 13502341.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.