Negativno usmerena kinezinska ATPaza
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| Negativno usmerena kinezinska ATPaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.4.5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Negativno usmerena kinezinska ATPaza (EC 3.6.4.5) je enzim sa sistematskim imenom kinezin ATP fosfohidrolaza (usmerena ka negativnom kraju).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim je strukturno skoro identičan sa enzimom EC 3.6.4.3 mada on katalizuje kretanje ka negativnom kraju mikrotubula.
Reference[uredi | uredi kod]
- ↑ Henningsen, U. and Schliwa, M. (1997). „Reversal in the direction of movement of a molecular motor”. Nature 389: 93-96. PMID 9288974.
- ↑ Sharp, D.J., Kuriyama, R., Essner, R. and Baas, P.W. (1997). „Expression of a minus-end-directed motor protein induces Sh9 cells to form axon-like processes with uniform microtubule polarity orientation”. J. Cell Sci. 110: 2373-2380. PMID 9410876.
- ↑ Sablin, E.P., CASe, R.B., Dai, S.C., Hart, C.L., Ruby, A., Vale, R.D. and Fletterick, R.J. (1998). „Direction determination in the minus-end-directed kinesin motor ncd”. Nature 395: 813-816. PMID 9796817.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.