NADPH dehidrogenaza (hinon)
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| NADPH dehidrogenaza (hinon) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.6.5.10 | ||||||||
| CAS broj | 37256-37-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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NADPH dehidrogenaza (hinon) (EC 1.6.5.10, redukovani nikotinamid adenin dinukleotid fosfat (hinon) dehidrogenaza, NADPH oksidaza, NADPH2 dehidrogenaza (hinon)) je enzim sa sistematskim imenom NADPH:(hinon-akceptor) oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim je flavoprotein. Enzim iz Escherichia coli je specifičan za NADPH i najaktivniji je na hinonskim derivatima.
Reference[uredi | uredi kod]
- ↑ Koli, A.K., Yearby, C., Scott, W. and Donaldson, K.O. (1969). „Purification and properties of three separate menadione reductases from hog liver”. J. Biol. Chem. 244: 621-629. PMID 4388793.
- ↑ Hayashi, M., Hasegawa, K., Oguni, Y. and Unemoto, T. (1990). „Characterization of FMN-dependent NADH-quinone reductase induced by menadione in Escherichia coli”. Biochim. Biophys. Acta 1035: 230-236. PMID 2118386.
- ↑ Hayashi, M., Ohzeki, H., Shimada, H. and Unemoto, T. (1996). „NADPH-specific quinone reductase is induced by 2-methylene-4-butyrolactone in Escherichia coli”. Biochim. Biophys. Acta 1273: 165-170. PMID 8611590.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.