N-acetilmuramoil-L-alaninska amidaza
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| N-acetilmuramoil-L-alaninska amidaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 3.5.1.28 | ||||||||
| CAS broj | 9013-25-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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N-acetilmuramoil-L-alaninska amidaza (EC 3.5.1.28, acetilmuramil-L-alaninska amidaza, N-acetilmuramil-L-alaninska amidaza, N-acilmuramil-L-alaninska amidaza, acetilmuramoil-alaninska amidaza, N-acetilmuraminska kiselina L-alaninska amidaza, acetilmuramil-alaninska amidaza, N-acetilmuramilalaninska amidaza, mureinska hidrolaza, N-acetilmuramoil-L-alaninska amidaza tip I, N-acetilmuramoil-L-alanin amidaza tip II) je enzim sa sistematskim imenom peptidoglikan amidohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza veza između N-acetilmuramoilnih ostataka i L-aminokiselinskih ostataka u pojedinim glikopeptidima ćelijskog zida
Reference[uredi | uredi kod]
- ↑ Ghuysen, J.-M., Dierickx, L., Coyette, J., Leyh-Bouille, M., Guinand, M. and Campbell, J.N. (1969). „An improved technique for the preparation of Streptomyces peptidases and N-acetylmuramyl-L-alanine amidase active on bacterial wall peptidoglycans”. Biochemistry 8: 213-222. PMID 5777325.
- ↑ Herbold, D.R. and Glaser, L. (1975). „Interaction of N-acetylmuramic acid L-alanine amidase with cell wall polymers”. J Biol Chem 250: 7231-7238. PMID 809432.
- ↑ Herbold, D.R. and Glaser, L. (1975). „Bacillus subtilis N-acetylmuramic acid L-alanine amidase”. J. Biol. Chem. 250: 1676-1682. PMID 803507.
- ↑ Ward, J.B., Curtis, C.A.M., Taylor, C. and Buxton, R.S. (1982). „Purification and characterization of two phage PBSX-induced lytic enzymes of Bacillus subtilis 168: an N-acetylmuramoyl-L-alanine amidase and an N-acetylmuramidase”. J. Gen. Microbiol. 128: 1171-1178. PMID 6126517.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.