Mitogenom-aktivirana proteinska kinaza kinaza

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Mitogenom-aktivirana proteinska kinaza kinaza
Identifikatori
EC broj 2.7.12.2
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Mitogenom-aktivirane proteinske kinaze kinaze (MAP2K) je enzim koji fosforiliše mitogenom-aktiviranu proteinsku kinazu (MAPK). MAP2K je klasifikovana kao EC 2.7.12.2.

Poznato je sedam gena:

Aktivatori p38 (MKK3 i MKK6), JNK (MKK4 i MKK7), i ERK (MEK1 i MEK2) kinaza definišu nezavisne MAP kinazne puteve prenosa signala.[1][2]

Reference[uredi - уреди]

  1. Dérijard B, et al. (1995). "Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms". Science 267 (5198): 682–5. doi:10.1126/science.7839144. PMID 7839144. 
  2. Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, Cobb MH (2001). "Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions". Endocr. Rev. 22 (2): 153–83. doi:10.1210/er.22.2.153. PMID 11294822. 

Literatura[uredi - уреди]

Spoljašnje veze[uredi - уреди]