Metilmalonil-KoA karboksitransferaza
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| Metilmalonil-KoA karboksitransferaza | |||||||||
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| Metilmalonil-KoA karboksitransferaza homohexamer, Propionibacterium | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.1.3.1 | ||||||||
| CAS broj | 9029-86-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Metilmalonil-KoA karboksitransferaza (EC 2.1.3.1, transkarboksilaza, metilmalonil koenzim A karboksiltransferaza, metilmalonil-KoA transkarboksilaza, oksalacetilna transkarboksilaza, metilmalonil-KoA karboksiltransferaza, metilmalonil-KoA karboksiltransferaza, (S)-2-metil-3-oksopropanoil-KoA:piruvat karboksiltransferaza, (S)-2-metil-3-oksopropanoil-KoA:piruvat karboksitransferaza karboksitransferaza) je enzim sa sistematskim imenom (S)-metilmalonil-KoA:piruvat karboksitransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (S)-metilmalonil-KoA + piruvat propanoil-KoA + oksaloacetat
Ovaj enzim je biotinilni protein, koji sadrži kobalt i cink.
Reference[uredi | uredi kod]
- ↑ Hoffmann, A., Hilpert, W. and Dimroth, P. (1989). „The carboxyltransferase activity of the sodium-ion-translocating methylmalonyl-CoA decarboxylase of Veillonella alcalescens”. Eur. J. Biochem. 179: 645-650. PMID 2920730.
- ↑ Swick, R.W. and Wood, H.G. (1960). „The role of transcarboxylation in propionic acid fermentation”. Proc. Natl. Acad. Sci. USA 46: 28-41. PMID 16590594.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.