Melperon

Melperon
(IUPAC) ime
	1-(4-fluorofenil)-4-(4-metil-1-piperidil)butan-1-on
Klinički podaci
AHFS/Drugs.com	Internacionalno ime leka
Identifikatori
CAS broj	3575-80-2
ATC kod	N05AD03
PubChem	15387
ChemSpider	14646
UNII	J8WA3K39B7
KEGG	D07309
Hemijski podaci
Formula	C16H22FNO
Mol. masa	263,35 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 ; Key: DKMFBWQBDIGMHM-UHFFFAOYSA-N
Farmakokinetički podaci
Metabolizam	Hepatički (inhibira CYP2D6)
Poluvreme eliminacije	3–4 časa (oralno); 6 časova (intramuskularno)
Farmakoinformacioni podaci
Trudnoća	?
Pravni status
Način primene	Oralno, intramuskularna injekcija

Melperon (Buronil, Burnil, Eunerpan) je atipični antipsihotik iz butirofenonske hemijske klase.

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Grözinger M, Dragicevic A, Hiemke C, Shams M, Müller MJ, Härtter S (2003). „Melperone is an inhibitor of the CYP2D6 catalyzed O-demethylation of venlafaxine”. Pharmacopsychiatry 36 (1): 3–6. DOI:10.1055/s-2003-38084. PMID 12649767.

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