Manoza-1-fosfat guanililtransferaza
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| Manoza-1-fosfat guanililtransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.13 | ||||||||
| CAS broj | 37278-24-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Manoza-1-fosfat guanililtransferaza (EC 2.7.7.13, GTP-manoza-1-fosfat guanililtransferaza, PIM-GMP (fosfomanoza izomeraza-guanozin 5'-difosfo-D-manoza pirofosforilaza), GDP-manoza pirofosforilaza, guanozin 5'-difosfo-D-manoza pirofosforilaza, guanozin difosfomanoza pirofosforilaza, guanozin trifosfat-manoza 1-fosfat guanililtransferaza, manoza 1-fosfat guanililtransferaza (guanozin trifosfat)) je enzim sa sistematskim imenom GTP:alfa-D-manoza-1-fosfat guanililtransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- GTP + alfa-D-manoza 1-fosfat difosfat + GDP-manoza
Bakterijski enzim takođe može da koristi ITP i dGTP kao donore.
Reference[uredi | uredi kod]
- ↑ Munch-Peterson, A. (1955). „Enzymatic synthesis and phosphorolysis of guanosine diphosphate mannose”. Arch. Biochem. Biophys. 55: 592-593.
- ↑ Preiss, J. and Wood, E. (1964). „Sugar nucleotide reactions in Arthrobacter. I. Guanosinediphosphate mannose pyrophosphorylase: purification and properties”. J. Biol. Chem. 239: 3119-3126. PMID 14245350.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.