Likopenska beta-ciklaza
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| Likopenska beta-ciklaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.5.1.19 | ||||||||
| CAS broj | 220801-82-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Likopenska beta-ciklaza (EC 5.5.1.19, CrtL, CrtL-b, CrtY) je enzim sa sistematskim imenom karotenoid beta-krajnja grupa lijaza (deciklizacija).[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- karotenoid psi-krajnja grupa karotenoid beta-krajnja grupa
Za dejstvo ovog enzima je neophodan NAD(P)H.
Reference[uredi | uredi kod]
- ↑ Cunningham, F.X., Jr., Chamovitz, D., Misawa, N., Gantt, E. and Hirschberg, J. (1993). „Cloning and functional expression in Escherichia coli of a cyanobacterial gene for lycopene cyclase, the enzyme that catalyzes the biosynthesis of β-carotene”. FEBS Lett. 328: 130-138. PMID 8344419.
- ↑ Cunningham, F.X., Jr., Sun, Z., Chamovitz, D., Hirschberg, J. and Gantt, E. (1994). „Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942”. Plant Cell 6: 1107-1121. PMID 7919981.
- ↑ Hugueney, P., Badillo, A., Chen, H.C., Klein, A., Hirschberg, J., Camara, B. and Kuntz, M. (1995). „Metabolism of cyclic carotenoids: a model for the alteration of this biosynthetic pathway in Capsicum annuum chromoplasts”. Plant J. 8: 417-424. PMID 7550379.
- ↑ Pecker, I., Gabbay, R., Cunningham, F.X., Jr. and Hirschberg, J. (1996). „Cloning and characterization of the cDNA for lycopene β-cyclase from tomato reveals decrease in its expression during fruit ripening”. Plant Mol. Biol. 30: 807-819. PMID 8624411.
- ↑ Hornero-Mendez, D. and Britton, G. (2002). „Involvement of NADPH in the cyclization reaction of carotenoid biosynthesis”. FEBS Lett. 515: 133-136. PMID 11943208.
- ↑ Maresca, J.A., Graham, J.E., Wu, M., Eisen, J.A. and Bryant, D.A. (2007). „Identification of a fourth family of lycopene cyclases in photosynthetic bacteria”. Proc. Natl. Acad. Sci. USA 104: 11784-11789. PMID 17606904.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.