Koenzim-B sulfoetiltiotransferaza

Izvor: Wikipedia
Koenzim-B sulfoetiltiotransferaza
Identifikatori
EC broj 2.8.4.1
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Koenzim-B sulfoetiltiotransferaza (EC 2.8.4.1, metil-KoM reduktaza, metil koenzim M reduktaza) je enzim sa sistematskim imenom metil-KoM:CoB S-(2-sulfoetil)tiotransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

metil-KoM + CoB \rightleftharpoons KoM-S-S-CoB + metan

Ovaj enzim katalizuje finalni korak metanogeneze.

Reference[uredi - уреди]

  1. Bobik, T.A., Olson, K.D., Noll, K.M. and Wolfe, R.S. (1987). "Evidence that the heterodisulfide of coenzyme-M and 7-mercaptanoylthreonine phosphate is a product of the methylreductase reaction in Methanobacterium". Biochem. Biophys. Res. Commun. 149: 455–460. PMID 3122735. 
  2. Ellermann, J., Hedderich, R., Boecher, R. and Thauer, R.K. (1988). "The final step in methane formation: investigations with highly purified methyl coenzyme M reductase component C from Methanobacterium thermoautotrophicum (strain Marburg)". Eur. J. Biochem. 184: 63–68. 
  3. Ermler, U., Grabarse, W., Shima, S., Goubeaud, M. and Thauer, R.K. (1997). "Crystal structure of methyl coenzyme M reductase: The key enzyme of biological methane formation". Science 278: 1457–1462. PMID 9367957. 
  4. Signor, L., Knuppe, C., Hug, R., Schweizer, B., Pfaltz, A. and Jaun, B. (2000). "Methane formation by reaction of a methyl thioether with a photo-excited nickel thiolate — a process mimicking methanogenesis in Archaea". Chemistry 6: 3508–3516. PMID 11072815. 
  5. Scheller, S., Goenrich, M., Boecher, R., Thauer, R.K. and Jaun, B. (2010). "The key nickel enzyme of methanogenesis catalyses the anaerobic oxidation of methane". Nature 465: 606–608. PMID 20520712. 

Literatura[uredi - уреди]

Spoljašnje veze[uredi - уреди]