Karboksipeptidaza E

Izvor: Wikipedia
Karboksipeptidaza E
Identifikatori
EC broj 3.4.17.10
CAS broj 81876-95-1
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Karboksipeptidaza E (EC 3.4.17.10, karboksipeptidaza H, enkefalinska konvertaza, kobaltom stimulisana hromafin granularna karboksipeptidaza, enkefalinska konvertaza, membranska karboksipeptidaza, enkefalinska prekursorska endopeptidaza, enkefalinska prekursorska karboksipeptidaza, peptidilna-L-lizin(-L-arginin) hidrolaza) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

Odvajanje C-terminalnog arginina ili lizina sa polipeptida

Ovaj cinkov enzim aktivira jon Co2+.

Reference[uredi - уреди]

  1. Qian, Y.M., Varlamov, O. and Fricker, L.D. (1999). "Glu300 of rat carboxypeptidase E is essential for enzymatic activity but not substrate binding or routing to the regulated secretory pathway". J. Biol. Chem. 274: 11582–11586. PMID 10206965. 
  2. Fricker, L.D. (1998). "Carboxypeptidase E/H". u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Academic Press. str. 1341-1344. 
  3. Fricker, L.D. (1995). "Methods for studying carboxypeptidase E". Methods Neurosci. 23: 237–250. 
  4. Manser, E., Fernandez, D. (1990). ", Loo,L., Goh, P.Y., Monfries, C., Hall, C. and Lim, L. Human carboxypeptidase E: isolation and characterisaton of the cDNA, sequence conservation, expression and processing in vitro". Biochem. J. 267: 517–525. PMID 2334405. 
  5. Fricker, L.D. (1988). "Carboxypeptidase E". Annu. Rev. Physiol. 50: 309–321. PMID 2897826. 

Literatura[uredi - уреди]

  • Fricker, L.D. (1998). "Carboxypeptidase E/H". u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Academic Press. str. 1341-1344. 

Spoljašnje veze[uredi - уреди]