Karboksilestaraza
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| Karboksilestaraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.1 | ||||||||
| CAS broj | 9016-18-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Karboksilestaraza (EC 3.1.1.1, ali-esteraza, B-esteraza, monobutiraza, kokainska esteraza, prokainska esteraza, metilbutiraza, vitamin A esteraza, butirilna esteraza, karboksiesteraza, karboksilatna esteraza, karboksilna esteraza, metilbutiratna esteraza, triacetinska esteraza, karboksil estarska hidrolaza, butiratna esteraza, metilbutiraza, alfa-karboksilesteraza, propionilna esteraza, nespecifična karboksilesteraza, esteraza D, esteraza B, esteraza A, serin esteraza, karboksilno kiselinska esteraza, kokainska esteraza) je enzim sa sistematskim imenom karboksilna-estar hidrolaza.[1][2][3][4][5][6][7][8] Ovaj enzim katalizuje sledeću hemijsku reakciju
- karboksilni estar + H2O alkohol + karboksilat
Ovaj enzim ima široku specifičnost.
Reference[uredi | uredi kod]
- ↑ Augusteyn, R.C., de Jersey, J., Webb, E.C. and Zerner, B. (1969). „On the homology of the active-site peptides of liver carboxylesterases”. Biochim. Biophys. Acta 171: 128-137. PMID 4884138.
- ↑ Barker, D.L. and Jencks, W.P. (1969). „Pig liver esterase. Physical properties”. Biochemistry 8: 3879-3889. PMID 4981346.
- ↑ Bertram, J. and Krisch, K. (1969). „Hydrolysis of vitamin A acetate by unspecific carboxylesterases from liver and kidney”. Eur. J. Biochem. 11: 122-126. PMID 5353595.
- ↑ Burch, J. (1954). „The purification and properties of horse liver esterase”. Biochem. J. 58: 415-426. PMID 13208632.
- ↑ Horgan, D.J., Stoops, J.K., Webb, E.C. and Zerner, B. (1969). „Carboxylesterases (EC 3.1.1). A large-scale purification of pig liver carboxylesterase”. Biochemistry 8: 2000-2006. PMID 5785220.
- ↑ Malhotra, O.P. and Philip, G. (1966). „Specificity of goat intestinal esterase”. Biochem. Z. 346: 386-402.
- ↑ Mentlein, R., Schumann, M. and Heymann, E. (1984). „Comparative chemical and immunological characterization of five lipolytic enzymes (carboxylesterases) from rat liver microsomes”. Arch. Biochem. Biophys. 234: 612-621. PMID 6208846.
- ↑ Runnegar, M.T.C., Scott, K., Webb, E.C. and Zerner, B. (1969). „Carboxylesterases (EC 3.1.1). Purification and titration of ox liver carboxylesterase”. Biochemistry 8: 2013-2018. PMID 5785222.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.