Hepacivirin

Izvor: Wikipedia
Hepacivirin
Identifikatori
EC broj 3.4.21.98
CAS broj 149885-80-3
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Hepacivirin (EC 3.4.21.98, Cpro-2, serinska proteinaza virusa hepatitis C NS3, NS3-4A serinski proteinazni kompleks) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

Hidroliza četiri peptidne veze u viralnim prekursornim poliproteinima, obično sa Asp ili Glu u P6 poziciji, Cys ili Thr u P1 i Ser ili Ala u P1'

Ovaj enzim je sadržan u genomu virusa iz hepatitis C grupe.

Reference[uredi - уреди]

  1. Kim, J.L., Morgenstern, K.A., Lin, C., Fox, T., Dwyer, M.D., Landro, J.A., Chambers, S.P., Markland, W., Lepre, C.A., O'Malley, E.T., Harbeson, S.L., Rice, C.M., Murcko, M.A., Caron, P.R. and Thomson, J.A. (1996). "Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide". Cell 87: 343–355. PMID 8861917. 
  2. Rice, C.M. (1998). "Hepatitis C virus polyprotein peptidase". u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Academic Press. str. 272-277. 

Literatura[uredi - уреди]

  • Rice, C.M. (1998). "Hepatitis C virus polyprotein peptidase". u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Academic Press. str. 272-277. 

Spoljašnje veze[uredi - уреди]