Glutation g-glutamilcisteiniltransferaza
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| Glutation g-glutamilcisteiniltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.2.15 | ||||||||
| CAS broj | 125390-02-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Glutation g-glutamilcisteiniltransferaza (EC 2.3.2.15, fitohelatinska sintaza, gama-glutamilcistein dipeptidilna transpeptidaza) je enzim sa sistematskim imenom glutation:poli(4-glutamil-cisteinil)glicin 4-glutamilcisteiniltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- glutation + [Glu(-Cys)]n-Gly Gly + [Glu(-Cys)]n+1-Gly
Reference[uredi | uredi kod]
- ↑ Grill, E., Löffler, S., Winnacker, E.-L. and Zenk, M.H. (1989). „Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific γ-glutamylcysteine dipeptidyl transpeptidase (phytochelatin synthase)”. Proc. Natl. Acad. Sci. USA 86: 6838-6842. PMID 16594069.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.