Fosfoketolaza
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| Fosfoketolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.2.9 | ||||||||
| CAS broj | 9031-75-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Fosfoketolaza (EC 4.1.2.9, D-ksiluloza-5-fosfat D-gliceraldehid-3-fosfat-lijaza (fosfatna acetilacija)) je enzim sa sistematskim imenom D-ksiluloza-5-fosfat D-gliceraldehid-3-fosfat-lijaza (dodaje fosfat; formira acetil-fosfat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-ksiluloza 5-fosfat + fosfat acetil fosfat + D-gliceraldehid 3-fosfat + H2O
Ovaj enzim je tiamin-difosfatni protein.
Reference[uredi | uredi kod]
- ↑ Heath, E.C., Hurwitz, J., Horecker, B.L. and Ginsburg, A. (1958). „Pentose fermentation by Lactobacillus plantarum. I. The cleavage of xylulose 5-phosphate by phosphoketolase”. J. Biol. Chem. 231: 1009-1029. PMID 13539033.
- ↑ Schramm, M., Klybas, V. and Racker, E. (1958). „Phospholytic cleavage of fructose-6-phosphate by fructose-6-phosphate phosphoketolase from Acetobacter xylinum”. J. Biol. Chem. 233: 1283-1288. PMID 13610828.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.