Dipeptidilna peptidaza I

Izvor: Wikipedija
Prijeđi na navigaciju Prijeđi na pretragu
Dipeptidilna peptidaza I
Heterododekamer katepsina C (čovjek)
Identifikatori
EC broj 3.4.14.1
CAS broj 9032-68-2
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Dipeptidilna peptidaza I (EC 3.4.14.1, katepsin C, dipeptidilna aminopeptidaza I, dipeptidilna transferaza, katepsin C, dipeptidilna transferaza, dipeptidna arilamidaza I, DAP I) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Odvajanje N-terminalnog dipeptida, Xaa-Yaa-Zaa-, izuzev kad je Xaa: Arg ili Lys, ili je Yaa: Zaa ili Pro

Ovaj enzim je zavistan od jona Cl-.

Reference[uredi | uredi kod]

  1. Planta, R.J., Gorter, J. and Gruber, M. (1964). „The catalytic properties of cathepsin C”. Biochim. Biophys. Acta 89: 511-519. PMID 14209333. 
  2. Metrione, R.M., Neves, A.G. and Fruton, J.S. (1966). „Purification and properties of dipeptidyl transferase (cathepsin C)”. Biochemistry 5: 1597-1604. PMID 5961281. 
  3. McDonald, J.K., Zeitman, B.B., Reilly, T.J. and Ellis, S. (1969). „New observations on the substrate specificity of cathepsin C (dipeptidyl aminopeptidase I) including the degradation of β-corticotropin and other peptide hormones”. J. Biol. Chem. 244: 2693-2709. PMID 4306035. 
  4. McDonald, J.K. and Schwabe, C. (1977). „Intracellular exopeptidases”. u: Barrett, A.J.. Proteinases in Mammalian Cells and Tissues. Amsterdam: North-Holland Publishing Co.. str. 311-391. 

Literatura[uredi | uredi kod]

  • McDonald, J.K. and Schwabe, C. (1977). „Intracellular exopeptidases”. u: Barrett, A.J.. Proteinases in Mammalian Cells and Tissues. Amsterdam: North-Holland Publishing Co.. str. 311-391. 

Spoljašnje veze[uredi | uredi kod]