Diamin oksidaza
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| Diamin oksidaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 1.4.3.22 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Diamin oksidaza (EC 1.4.3.22, aminska oksidaza (nespecifična), CAO (nespecifična), Cu-sadržavajuća aminska oksidaza (nespecifična), bakarna aminska oksidaza (nespecifična), diaminska oksidaza (nespecifična), diamino oxhidraza (nespecifična), histaminaza, semikarbazid-senzitivna aminska oksidaza) je enzim sa sistematskim imenom histamin:kiseonik oksidoreduktaza (deaminacija).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- histamin +H2O + O2 (imidazol-4-il)acetaldehid + NH3 +H2O2
Ova grupa enzima oksiduje diamine, kao što je histamin, kao i neke primarne monoamine.
Reference[uredi | uredi kod]
- ↑ Zeller, E.A. (1963). „Diamine oxidases”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 8 (2nd izd.). New York: Academic Press. str. 313-335.
- ↑ Crabbe, M.J., Waight, R.D., Bardsley, W.G., Barker, R.W., Kelly, I.D. and Knowles, P.F. (1976). „Human placental diamine oxidase. Improved purification and characterization of a copper- and manganese-containing amine oxidase with novel substrate specificity”. Biochem. J. 155: 679-687. PMID 182134.
- ↑ Chassande, O., Renard, S., Barbry, P. and Lazdunski, M. (1994). „The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter”. J. Biol. Chem. 269: 14484-14489. PMID 8182053.
- ↑ Houen, G. (1999). „Mammalian Cu-containing amine oxidases (CAOs): new methods of analysis, structural relationships, and possible functions”. APMIS Suppl. 96: 1-46. PMID 10668504.
- ↑ Elmore, B.O., Bollinger, J.A. and Dooley, D.M. (2002). „Human kidney diamine oxidase: heterologous expression, purification, and characterization”. J. Biol. Inorg. Chem. 7: 565-579. PMID 12072962.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.