Diacilglicerol O-aciltransferaza

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Diacilglicerol O-aciltransferaza
Identifikatori
EC broj 2.3.1.20
CAS broj 9029-98-5
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Diacilglicerol O-aciltransferaza (EC 2.3.1.20, digliceridna aciltransferaza, 1,2-diacilglicerolna aciltransferaza, diacilglicerolna aciltransferaza, digliceridna O-aciltransferaza, palmitoil-KoA-sn-1,2-diacilglicerol aciltransferaza, acil-KoA:1,2-diacilglicerol O-aciltransferaza) je enzim sa sistematskim imenom acil-KoA:1,2-diacil-sn-glicerol O-aciltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

acil-KoA + 1,2-diacil-sn-glicerol \rightleftharpoons KoA + triacilglicerol

Palmitoil-KoA i drugi dugolančani acil-KoAs mogu da deluju kao donori.

Reference[uredi - уреди]

  1. Coleman, R. and Bell, R.M. (1976). "Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols". J. Biol. Chem. 251: 4537–4543. PMID 947894. 
  2. Grigor, M.R. and Bell, R.M. (1982). "Separate monoacylglycerol and diacylglycerol acyltransferases function in intestinal triacylglycerol synthesis". Biochim. Biophys. Acta 712: 464–472. PMID 6289909. 
  3. Kawasaki, T. and Snyder, F. (1988). "Synthesis of a novel acetylated neutral lipid related to platelet-activating factor by acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol acyltransferase in HL-60 cells". J. Biol. Chem. 263: 2593–2596. PMID 3422635. 
  4. Weiss, S.B., Kennedy, E.P. and Kiyasu, J.Y. (1960). "The enzymatic synthesis of triglycerides". J. Biol. Chem. 235: 40–44. PMID 13843753. 

Literatura[uredi - уреди]

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