Bis-g-glutamilcistin reduktaza
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| Bis-g-glutamilcistin reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.1.13 | ||||||||
| CAS broj | 117056-54-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Bis-g-glutamilcistin reduktaza (EC 1.8.1.13, NADPH2:bis-gama-glutamilcisteinska oksidoreduktaza) je enzim sa sistematskim imenom gama-glutamilcistein:NADP+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2 gama-glutamilcistein + NADP+ bis-gama-glutamilcistin + NADPH + H+
Ovaj enzim je visoko specifičan.
Reference[uredi | uredi kod]
- ↑ Sundquist, A.R. and Fahey, R.C. (1988). „The novel disulfide reductase bis-γ-glutamylcystine reductase and dihydrolipoamide dehydrogenase from Halobacterium halobium: purification by immobilized-metal-ion affinity chromatography and properties of the enzymes”. J. Bacteriol. 170: 3459-3467. PMID 3136140.
- ↑ Sundquist, A.R. and Fahey, R.C. (1989). „The function of γ-glutamylcysteine and bis-γ-glutamylcystine reductase in Halobacterium halobium”. J. Biol. Chem. 264: 719-725. PMID 2910862.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.