Bis(5'-nukleozil)-tetrafosfataza (asimetrična)
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| Bis(5'-nukleozil)-tetrafosfataza (asimetrična) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.1.17 | ||||||||
| CAS broj | 37289-29-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Bis(5'-nukleozil)-tetrafosfataza (asimetrična) (EC 3.6.1.17, bis(5'-guanozil)-tetrafosfataza, bis(5'-adenozil)-tetrafosfataza, diguanozintetrafosfataza (asimetrična), dinukleozidtetrafosfataza (asimetrična), diadenozin P1,P4-tetrafosfataza, dinukleozidna tetrafosfataza, 1-P,4-P-bis(5'-nukleozil)-tetrafosfatna nukleotidohidrolaza) je enzim sa sistematskim imenom P1,P4-bis(5'-nukleosil)-tetrafosfat nukleotidohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- P1,P4-bis(5'-guanozil) tetrafosfat + H2O GTP + GMP
Ovaj enzim takođe deluje na bis(5'-ksantozil)-tetrafosfat i, manjom brzinom, na bis(5'-adenozil)-tetrafosfat i bis(5'-uridil)-tetrafosfat.
Reference[uredi | uredi kod]
- ↑ Jakubowski, H. and Guranowski, A. (1983). „Enzymes hydrolyzing ApppA and/or AppppA in higher plants. Purification and some properties of diadenosine triphosphatase, diadenosine tetraphosphatase, and phosphodiesterase from yellow lupin (Lupinus luteus) seeds”. J. Biol. Chem. 258: 9982-9989. PMID 6309793.
- ↑ Vallejo, C.M., Lobatón, C.D., Quintanilla, M., Sillero, A. and Sillero, M.A.G. (1976). „Dinucleosidasetetraphosphatase in rat liver and Artemia salina”. Biochim. Biophys. Acta 438: 304-309. PMID 181087.
- ↑ Warner, A.H. and Finamore, F.J. (1965). „Isolation, purification, and characterization of P1,P4-diguanosine 5′-tetraphosphate asymmetrical-pyrophosphohydrolase from brine shrimp eggs”. Biochemistry 4: 1568-1575. PMID 4955726.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.