Beta-litička metaloendopeptidaza
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Beta-litička metaloendopeptidaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.4.24.32 | ||||||||
CAS broj | 37288-92-9 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Beta-litička metaloendopeptidaza (EC 3.4.24.32, Myxobacter beta-litička proteinaza, ahromopeptidazna komponenta, beta-litička metaloproteinaza, beta-litička proteaza, Myxobakterija sorangium beta-litička proteinaza, Myxobacter495 beta-litička proteinaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Razlaganje N-acetilmuramoil-Ala}, i lanca insulina B u Gly23-Phe > Val18-Cys
Ovaj ezim je prisutan u Achromobacter lyticus i Lysobacter enzymogenes.
Reference[uredi | uredi kod]
- ↑ Whitaker, D.R., Roy, C., Tsai, C.S. and Juraöek, L. (1965). „Lytic enzymes of Sorangium sp. A comparison of the proteolytic properties of the α- and β-lytic proteases”. Can. J. Biochem. 43: 1961-1970. PMID 5880182.
- ↑ Whitaker, D.R. and Roy, C. (1967). „Concerning the nature of the α- and β-lytic proteases of Sorangium sp”. Can. J. Biochem. 45: 911-911. PMID 6034704.
- ↑ Li, S. (1990). „L., Norioka, S. and Sakiyama, F. Molecular cloning and nucleotide sequence of the β-lytic protease gene from Achromobacter lyticus”. J. Bacteriol. 172: 6506-6511. PMID 2228973.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.